Marmoset PFC Connectome

Exploring Connectional Architecture of the Prefrontal Cortex (PFC)

Prefrontal cortex (PFC) plays a central role in orchestrating various cognitive functions and evolved greatly in primate lineage. The understanding of its connectional architecture in a primate model is, therefore, critical in extrapolating the animal data to humans. Here we report a brain-wide, connectomics mapping of the marmoset PFC projections using serial two-photon tomography imaging.

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Citation and License

Watakabe Akiya, Skibbe Henrik : Brain/MINDS Marmoset PFC Connectome (DataID: 6358)


Creative Commons Attribution License logo The published data is licensed under a Creative Commons Attribution 4.0 International License.

Related publications :

Watakabe A, Skibbe H, Nakae K, Abe H, Ichinohe N, Rachmadi MF, Wang J, Takaji M, Mizukami H, Woodward A, Gong R, Hata J, Van Essen DC, Okano H, Ishii S, Yamamori T.
Local and long-distance organization of prefrontal cortex circuits in the marmoset brain.
Neuron. 2023 May 9, S0896-6273(23)00338-0.


H. Skibbe, M.F. Rachmadi, K. Nakae, C. E. Gutierrez, J. Hata, H. Tsukada, C. Poon, K. Doya, P. Majka, M. G. P. Rosa, H. Okano, T. Yamamori, S. Ishii, M. Reisert, A. Watakabe.
The Brain/MINDS Marmoset Connectivity Atlas: Exploring bidirectional tracing and tractography in the same stereotaxic space.
bioRxiv 2022;


Contributors and Acknowledgements :

Laboratory for Molecular Analysis of Higher Brain Function (closed in 2023) : Experiments.

Brain Image Analysis Unit : Image processing.

Connectome Analysis Unit : Viewer development, atlasing, hosting.

As part of Brain/MINDS project, this work was supported by Japan Agency for Medical Research and Development (AMED).