1. International Research Center for Neurointelligence (WPI-IRCN), UTIAS, The University of Tokyo 2. Institute of Innovative Research, Tokyo Institute of Technology 3. RIKEN Center for Brain Science 4. Department of Ultrastructural Research, National Center of Neurology and Psychiatry 5. Department of Preventive Intervention for Psychiatric Disorders, National Center of Neurology and Psychiatry
We adopted a Local-Global paradigm. Two tones with different pitches (Tone A = 800Hz; Tone B = 1600Hz) were synthesized. Each tone was 50 ms in duration. Series of five tones were presented with a 150 ms inter-tone interval, with 950-1150 ms was set between the offset of the last tone of a sequence and the onset of the first tone of the following sequence (see Figure 1A). Four different stimulus blocks were used: AAAAA, BBBBB, AAAAB, and BBBBA blocks. In AAAAA blocks, 20 AAAAA sequences were delivered, followed by a random mixture of 64 AAAAA and 16 AAAAB. In BBBBB blocks, 20 BBBBB sequences were delivered, followed by a random mixture of 64 BBBBB and 16 BBBBA. In AAAAB blocks, 20 AAAAB sequences were delivered, followed by a random mixture of 64 AAAAB and 16 AAAAA. In BBBBA blocks, 20 BBBBA sequences were delivered, followed by a random mixture of 64 BBBBA and 16 BBBBB. In each experimental day, we conducted ECoG recordings on 1~8 blocks, depending on the animal’s condition. For each animal, we performed 7-9 recordings for each block. Epidural ECoG recordings were taken in the passive listening condition while monkeys were awake.ECoG data were sampled at 1KHz (for Monkey Ji and Rc) or 1017.25Hz (for Monkey Yo, Ca, and Rm).
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Chao ZC; Komatsu M; Matsumoto M; Iijima K; Nakagaki K; Ichinohe N (2024): Diverse Configurations of Erroneous Predictive Coding Across Brain Hierarchies in a Non-Human Primate Model of Autism Spectrum Disorder. Biological Communications 7(1), 851.
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